Tag: mononuclear cell

My Canadian Pharmacy

Outcomes of Lidocaine Effects on Immunocompetent Cells

Previous studies have suggested that lidocaine has profound effects on both the structure and function of immunocompetent cells. Lidocaine has been shown to reversibly inhibit alveolar macrophage hexose monophosphate shunt activity in a dose-dependent fashion if cells are exposed for 20 minutes or less. Other studies performed on human peripheral blood mononuclear cell populations have demonstrated inhibition of mitogenic responses to PH A and decreased