What is Ventolin Inhaler?
What is Ventolin Inhaler?
Ventolin inhaler is beta 2- selective adrenoreceptor agonists. In therapeutic doses, Ventolin inhaler performs on beta 2-adrenergic receptors of bronchial smooth muscles, providing little or no effect on beta1-adrenergic myocardium receptors.
Canadian Pharmacy Ventolin has a pronounced bronchodilator effect for:
- preventing or arresting bronchospasm and asthma attack;
- reducing resistance in the airways;
- increasing vital capacity (VC);
- increasing mucociliary clearance (in chronic bronchitis to 36%);
- stimulating mucous secretion;
- activating ciliated epithelium function.
At recommended daily dose of ventolin, this inhaler has no adverse effect on cardiovascular system, it does not cause blood pressure increase.
To lesser extent, as compared with drugs of this group Ventolin generic has a positive chrono – and inotropic effects. Ventolin inhaler causes coronary arteries extension.Generic Ventolin has a number of metabolic effects:
- reducing concentration of potassium in plasma;
- affecting glycogenolysis and insulin release;
- having hyperglycemic (especially in patients with bronchial asthma) and lipolytic effect;
- increasing acidosis risk.
After inhaled forms application, Ventolin effect develops rapidly, beginning – after 5 minutes, maximum – after 30-90 minutes (75% of the maximum effect is achieved within 5 minutes), Ventolin effect duration – 4-6 hours.
Ventolin Pharmaceutical Forms and Package
Ventolin obtains the following pharmaceutical form – metered aerosol for inhalation which contains a drug for 240 doses. Ventolin online can be purchased in form of aluminum inhaler with metering plastic device. Protective cap is made of the same material. The aerosol of Ventolin is packaged in a pack made of cardboard. Inhaler is comprised of white suspension.
The active substance is drug suspension required amount of micronised albuterol sulphate, propellant that completed, which is contained in a single dose – 75 mg, and in a single inhaler to eighteen grams.
Ventolin Term and Storage Conditions
Ventolin shelf-life is 2 years, in case if it is not influenced by UV light and freezing. Acceptable storage temperature should not exceed thirty degrees. Keep out of reach of children.
My Canadian Pharmacy Ventolin Pharmacology
As a bronchodilator drug – beta 2-agonists, Ventolin has a bronchodilatory effect on bronchial smooth muscles. Adrenergic receptors on myocardium have practically no effect or it is absolutely insignificant. By means of its action Ventolin inhaler relieves and prevents bronchospasm, decreases airway resistance and increases lung capacity.
When chronic bronchitis and asthma, Ventolin increases mucociliary clearance up to 36 percent. Its action is achieved due to stimulation of mucus secretion and activation of ciliated epithelium function.
Ventolin application at recommended doses does not adversely affect either cardiovascular system or blood pressure rate.
With its use expansion of coronary arteries and increase severity of metabolic effects may occur:
- decrease in blood potassium concentration of plasma;
- influence on insulin production and glycogenolysis;
- providing lipolytic effect;
- increase in acid-balance.
After Ventolin inhalation, no more than 20% of dose reaches lower respiratory tract. Remaining drug may stay in oral cavity, hitting throat and then gastrointestinal tract. That drug portion that came to destination, is absorbed into blood and lung tissue, but is not subjected to metabolism.
That part that penetrates digestive system during absorption, immediately becomes subject to intensive metabolic processes in liver to form inactive phenol sulfate. Ventolin binds to plasma by 10 percent.
Implementing intravenous salbutamol (Ventolin inhaler) application, its half-life lasts from 4 to 6 hours. Ventolin withdrawal takes place by means of kidneys in urine partially in form of phenol sulfate. Ventolin main component – Salbutamol – is slightly excreted with feces. The main part of active Ventolin substance introduced into body in any way, will be excreted not earlier than in three days.
Indications for Ventolin use
Ventolin inhaler is indicated for those patients who suffer from asthma in the following cases:
- if necessary, expressed relief of asthma attacks, especially in period of acute severe disease nature;
- prevent bronchospasm attack that caused by exposure to allergens or high physical activity;
- if necessary, use as one of constituent drugs in long-term maintenance therapy of complex nature.
Ventolin inhaler online can be administered as aerosol for use in chronic obstructive pulmonary tract obstruction accompanied by reversible airway, as well as chronic bronchitis.
Ventolin is universal short-acting inhaler for asthma attacks treatment as well as asthma prevention. You may buy Ventolin inhaler via My Canadian Pharmacy: my-medstore-canada.net at attractively low price moreover you may get bonuses and discounts available at our online pharmacy.